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Protein Coding Gene : Mvk mevalonate kinase
Primary Identifier  MGI:107624 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  17855
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables mevalonate kinase activity. Predicted to be involved in several processes, including cholesterol biosynthetic process; isopentenyl diphosphate biosynthetic process, mevalonate pathway; and negative regulation of translation. Predicted to act upstream of or within cholesterol metabolic process and sterol biosynthetic process. Predicted to be located in peroxisome. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in lipid metabolism disorder; mevalonic aciduria; and porokeratosis. Orthologous to human MVK (mevalonate kinase).
  • synonyms:
  • expressed sequence AI414037,
  • MGD-MRK-36198,
  • expressed sequence AI256848,
  • AI256848,
  • Mvk,
  • MGI:1917348,
  • MGI:2140856,
  • MGI:2140825,
  • mevalonate kinase,
  • RIKEN cDNA 2310010A05 gene,
  • AI414037,
  • 2310010A05Rik
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





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