|  Help  |  About  |  Contact Us

Protein Coding Gene : Trarg1 trafficking regulator of GLUT4 (SLC2A4) 1

Primary Identifier  MGI:3029307 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  237858
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in endosome to plasma membrane protein transport and glucose import in response to insulin stimulus. Acts upstream of or within establishment of localization in cell and vesicle fusion to plasma membrane. Located in cytoplasmic vesicle membrane; perinuclear region of cytoplasm; and plasma membrane. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; nervous system; sensory organ; and white fat. Orthologous to human TRARG1 (trafficking regulator of GLUT4 (SLC2A4) 1).
PHENOTYPE: Mice homozygous for a knock-out allele display abnormal adipocyte glucose uptake and show increased body weight, elevated blood insulin and glucose levels, and insulin resistance when fed a high-fat diet. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA C130069F04 gene,
  • tumor suppressor candidate 5,
  • C130069F04Rik,
  • Tusc5,
  • trafficking regulator of GLUT4 (SLC2A4) 1,
  • Trarg1,
  • LOST1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For