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Allele : Tnf<tm1Jods> tumor necrosis factor; targeted mutation 1, Johnathon D Sedgwick

Primary Identifier  MGI:1860953 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tnf
Inheritance Mode  Not Specified Transmission  Germline
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
description  ES cell lines = BL/6-III and Bruce 4
molecularNote  905 base pairs, encompassing exons 2, 3, and a portion of exon 4, were replaced with a neomycin selection cassette. RT-PCR confirmed the absence of transcript in homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • TNF -,
  • TNFalpha<->,
  • TNFalpha<->,
  • TNF<->,
  • TNF<->,
  • TNF-KO,
  • TNF -,
  • TNF-KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

91 Publication categories

Trail: Allele