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Protein Domain : ABI family

Primary Identifier  IPR028457 Type  Family
Short Name  ABI
description  This entry represents the ABI family, which includes Abi1, Abi2 and Abi3. They are SH3 domain-containing proteins that are involved in regulation of actin organisation. Abi1, Abi2 and Abi3 all participate in the formation of the Abi/WAVE complex, which regulates Arp2/3-mediated actin filament nucleation and actin network assembly [, , ]. This entry also include Abl interactor homologue (abiA) from Dictyostelium discoideum (Slime mold). abiA is part of a Scar/WAVE complex that is required for proper cytokinesis [].

3 Child Features

0 Parent Features

53 Protein Domain Regions