Primary Identifier | MGI:2445123 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 218460 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of autophagy. Predicted to act upstream of or within autophagy. Located in cytoplasm. Orthologous to human WDR41 (WD repeat domain 41). PHENOTYPE: Mice homozygous for an ENU-generated allele exhibit increased susceptibility to DDS-induced colitis with increased activated single positive T cells. [provided by MGI curators] |