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Allele : Fzd3<tm1Nat> frizzled class receptor 3; targeted mutation 1, Jeremy Nathans

Primary Identifier  MGI:2388632 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Fzd3
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The coding regions of the exons 1 and 2 were replaced with a cassette containing lacZ and neo genes. The deleted region encoded the amino terminal signal sequence and a conserved extracellular domain that has been previously been shown to be involved wiht Wnt binding. The expression pattern of beta-galactosidase replicated that of the endogenous gene.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • fz3(-),
  • fz3(-)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

24 Publication categories

Trail: Allele