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Protein Coding Gene : Foxo4 forkhead box O4

Primary Identifier  MGI:1891915 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  54601
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables sequence-specific DNA binding activity. Acts upstream of or within mitotic G2 DNA damage checkpoint signaling; negative regulation of cell population proliferation; and positive regulation of DNA-templated transcription. Predicted to be located in cytosol and nuclear speck. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; early embryo; genitourinary system; inner cell mass; and sensory organ. Orthologous to human FOXO4 (forkhead box O4).
PHENOTYPE: Mice hemizygous and homozygous for a knock-out allele are viable, fertile and grossly normal with no detectable histological abnormalities in most tissues. [provided by MGI curators]
  • synonyms:
  • afx,
  • myeloid/lymphoid or mixed lineage-leukemia translocation to 7 homolog (Drosophila),
  • Afxh,
  • forkhead box O4,
  • Mllt7,
  • Foxo4

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

15 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For