Primary Identifier | MGI:3708903 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Sebox |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was used to flank the entire gene with loxP sites and insert a Frt-flanked PGK-neomycin resistance cassette in reverse orientation. The gene was deleted by crossing these mice to a germline Cre strain, and subsequently mated to a line of germline Flp recombinase expressing mice, leaving a single loxP and an Frt site. No gene expression is detected by RNA-ISH. |