Primary Identifier | MGI:3625623 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ddo |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 3 was replaced with a neomycin resistance cassette by homologous recombination. The targeting event introduced a frame shift. Northern blot failed to detect transcript in mutant liver and kidney. Western blot confirmed absence of protein, as well. |