| Primary Identifier | MGI:3770513 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Tln1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Coding exons one through four (second through fifth exons) are flanked by loxP sites. This allele was generated by in vivo, Cre recombinase-mediated deletion of a loxP-flanked neomycin resistance cassette from the first intron of Tln1tm4Crit in cre transgenic embryos homozygous for the latter allele (personal communication). Talin expression can be ablated in specific cell/tissue types by crossing homozygous mice with appropriate cre transgenic mice. |
