First Author | Miura N | Year | 1993 |
Journal | FEBS Lett | Volume | 326 |
Issue | 1-3 | Pages | 171-6 |
PubMed ID | 8325367 | Mgi Jnum | J:33942 |
Mgi Id | MGI:81422 | Doi | 10.1016/0014-5793(93)81785-x |
Citation | Miura N, et al. (1993) MFH-1, a new member of the fork head domain family, is expressed in developing mesenchyme. FEBS Lett 326(1-3):171-6 |
abstractText | We have isolated a novel mouse gene, MFH-1 (mesenchyme fork head 1) that is related to the Drosophila fork head and rat HNF3 genes. MFH-1 encodes a distinct fork head domain that is classified into a distinct subfamily. A recombinant MFH-1 protein could bind to the HNF3 binding site. MFH-1 is expressed temporally in developing embryos, first in the non-notochordal mesoderm and later in areas of mesenchymal condensation in the trunk, head, and limbs. Our results suggest that MFH-1 might be involved in the formation of special mesenchymal tissues. |