| Primary Identifier | MGI:104742 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 16519 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable inward rectifier potassium channel activity and voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential. Predicted to be involved in potassium ion import across plasma membrane and regulation of monoatomic ion transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport. Is active in parallel fiber to Purkinje cell synapse and presynaptic membrane. Is expressed in several structures, including adrenal gland; alimentary system; brain; male reproductive gland or organ; and thymus. Orthologous to human KCNJ3 (potassium inwardly rectifying channel subfamily J member 3). PHENOTYPE: Mice homozygous for a targeted null mutation display slightly increased resting heart rates, and blunted responses to both indirect vagal activation and direct adenosine A1 receptor activation (intended to activate the muscarinic-gated atrial potassium channel). [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
