Primary Identifier | MGI:3044786 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Rgs1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neo gene was inserted into exon 1 via homologous recombination disrupting the first coding exon and exon splice donor site. Immunoblotting of B-cell lysates after immunization confirmed the absence of protein expression in homozygous mice. Expression of clustered and related Rgs genes was unaffected. |