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Protein Coding Gene : Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
Primary Identifier  MGI:1914928 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  67678
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable U6 snRNA 3'-end binding activity. Predicted to be involved in P-body assembly and mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of Lsm1-7-Pat1 complex; Lsm2-8 complex; and nucleus. Predicted to be active in P-body. Is expressed in central nervous system and sensory organ. Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated).
PHENOTYPE: MIce homozygous for an allele that only expresses variant 1 exhibit decreased susceptibility to VSV and influenza infection. [provided by MGI curators]
  • synonyms:
  • MGI:1917279,
  • RIKEN cDNA 6030401D18 gene,
  • SMX4,
  • LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated,
  • 6030401D18Rik,
  • 1010001J12Rik,
  • USS2,
  • MGI:2442209,
  • RIKEN cDNA 2610005D18 gene,
  • Lsm3,
  • RIKEN cDNA 1010001J12 gene,
  • 2610005D18Rik
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1 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Function

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Interactions

6 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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