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Protein Coding Gene : Ralgds ral guanine nucleotide dissociation stimulator

Primary Identifier  MGI:107485 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  19730
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be located in brush border; cytosol; and nucleus. Predicted to be active in plasma membrane. Is expressed in several structures, including blastocyst; early embryo; nervous system; ovary; and retina. Orthologous to human RALGDS (ral guanine nucleotide dissociation stimulator).
PHENOTYPE: Homozygous mutant mice exhibit reduced tumor incidence, size and progression to malignancy in multistage skin carcinogenesis. [provided by MGI curators]
  • synonyms:
  • Gnds,
  • mKIAA1308,
  • ral guanine nucleotide dissociation stimulator,
  • Ralgds,
  • MGD-MRK-36053,
  • Rgds,
  • RalGDS

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

10 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For