| Primary Identifier | IPR028530 | Type | Family |
| Short Name | Vav1 |
| description | Vav protein family members are multiple domain proteins, including Vav from flies and Vav1/2/3 from mammals. They have a calponin homology (CH) domain, an acidic domain (AC), a Dbl homology (DH) domain, a pleckstrin homology (PH) domain, a cysteine-rich (CR) domain containing a zinc finger, and a compound domain having SH2 and SH3 domains. Therefore they may participate in the activity of several pathways [, ]. They are signal transducer proteins that couple tyrosine kinase signals with the activation of the Rho/Rac GTPases, [, , ]. This entry includes mammalian Vav1 and its homologues. |
