Primary Identifier | MGI:5523793 | Allele Type | Spontaneous |
Attribute String | Null/knockout | Gene | Mir429 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
description | This allele was generated in ES cells containing Mir200btm1.1Osb. |
molecularNote | A point mutation (U-to-C in miRNA, A-to-G in forward genomic) mutated a residue critical for mature microRNA expression. Northern blot analysis confirmed the absence of microRNA expression. Expression of Mir200a is normal. |