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Protein Coding Gene : Parp14 poly (ADP-ribose) polymerase family, member 14
Primary Identifier  MGI:1919489 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  547253
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including NAD+ binding activity; pentosyltransferase activity; and transcription corepressor activity. Involved in negative regulation of type II interferon-mediated signaling pathway and positive regulation of interleukin-4-mediated signaling pathway. Located in cytoplasm. Is expressed in hemolymphoid system; intestine; and urogenital sinus. Orthologous to human PARP14 (poly(ADP-ribose) polymerase family member 14).
PHENOTYPE: Mice homozygous for a gene trap allele exhibit altered B cell subsets and inability to respond to the apoptosis protective affects of IL4. [provided by MGI curators]
  • synonyms:
  • MGC:29390,
  • BC021340,
  • poly (ADP-ribose) polymerase family, member 14,
  • collaborator of Stat6,
  • RIKEN cDNA 1600029O10 gene,
  • 1600029O10Rik,
  • Parp14,
  • cDNA sequence BC021340,
  • CoaSt6,
  • MGI:2385040
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Trail: ProteinCodingGene

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