| Primary Identifier | IPR035775 | Type | Domain |
| Short Name | CD2AP_SH3_1 |
| description | CD2AP is a multifunctional adaptor protein involved in membrane trafficking, dynamic actin remodelling and endocytosis [, ]. CD2AP contains three SH3 domains, a proline-rich region, and a C-terminal coiled-coil domain. Different biological processes regulated by CD2AP require specific binding partners [].This entry represents the first SH3 domain (SH3A). It binds to the PXXXPR motif present in c-Cbl and the cytoplasmic domain of cell adhesion protein CD2 []. |
