| Primary Identifier | IPR040196 | Type | Family |
| Short Name | ZP3 |
| description | At fertilization, mammalian sperm binds to the extracellular zona pellucida that surrounds ovulated eggs. The zona pellucida is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4 []. Fish eggs are also surrounded by an envelope, which consists of a few proteins homologous to mammalian ZP1, ZP3, and ZP4 [, ]. Glycoprotein ZP3 is essential for normal fertility []. It promotes fertilization by recognizing sperm binding and activating the acrosome reaction [, ]. It is also required for germinal vesicle breakdown in oocyte meiosis []. |
