First Author | Fukuda K | Year | 1993 |
Journal | FEBS Lett | Volume | 327 |
Issue | 3 | Pages | 311-4 |
PubMed ID | 8394245 | Mgi Jnum | J:34453 |
Mgi Id | MGI:81911 | Doi | 10.1016/0014-5793(93)81011-n |
Citation | Fukuda K, et al. (1993) Primary structures and expression from cDNAs of rat opioid receptor delta- and mu-subtypes. FEBS Lett 327(3):311-4 |
abstractText | The complete amino acid sequences of rat opioid receptors (designated as ROR-A and ROR-B) have been deduced by cloning and sequencing the cDNAs. The ligand-binding properties of ROR-A and ROR-B expressed from the cloned cDNAs in Chinese hamster ovary cells correspond most closely to those of the pharmacologically defined delta- and mu-opioid receptor subtypes, respectively. RNA blot hybridization analysis revealed that cerebrum and brainstem contain both ROR-A and ROR-B mRNAs, whereas neither ROR-A nor ROR-B mRNAs can be detected in cerebellum. |