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Publication : Primary structures and expression from cDNAs of rat opioid receptor delta- and mu-subtypes.

First Author  Fukuda K Year  1993
Journal  FEBS Lett Volume  327
Issue  3 Pages  311-4
PubMed ID  8394245 Mgi Jnum  J:34453
Mgi Id  MGI:81911 Doi  10.1016/0014-5793(93)81011-n
Citation  Fukuda K, et al. (1993) Primary structures and expression from cDNAs of rat opioid receptor delta- and mu-subtypes. FEBS Lett 327(3):311-4
abstractText  The complete amino acid sequences of rat opioid receptors (designated as ROR-A and ROR-B) have been deduced by cloning and sequencing the cDNAs. The ligand-binding properties of ROR-A and ROR-B expressed from the cloned cDNAs in Chinese hamster ovary cells correspond most closely to those of the pharmacologically defined delta- and mu-opioid receptor subtypes, respectively. RNA blot hybridization analysis revealed that cerebrum and brainstem contain both ROR-A and ROR-B mRNAs, whereas neither ROR-A nor ROR-B mRNAs can be detected in cerebellum.
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