| Type | MGI:General | Description | marked nuclear pleomorphism and cell size variation are seen 13 weeks of age after stopping NTBC treatment after stopping treatment mice display dysplastic hepatocytes show nuclear pleomorphism with enlarged nucleoli and intranuclear lipid, cytoplasmic disorganization, focally enlarged mitochondria with paracrystalline arrays, elongated and tortuous cristae or loss of cristae and multiple clusters of aggregated intermediated filaments in the cytoplasm |
