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Protein Domain : MCM N-terminal domain

Primary Identifier  IPR027925 Type  Domain
Short Name  MCM_N
description  This entry represents the N-terminal region of MCM proteins. This region is composed of three structural domains. Firstly a four helical bundle, secondly a zinc binding motif and thirdly an OB-like fold [].MCM proteins are DNA-dependent ATPases required for the initiation ofeukaryotic DNA replication [, , ]. In eukaryotes there is a family of six proteins, MCM2 to MCM7. They were first identified in yeast where most of them have adirect role in the initiation of chromosomal DNA replication by interacting directly with autonomously replicating sequences (ARS). They were thus called minichromosome maintenance proteins, MCM proteins [].

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26 Protein Domain Regions