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Protein Coding Gene : Plppr4 phospholipid phosphatase related 4

Primary Identifier  MGI:106530 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  229791
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable lysophosphatidic acid phosphatase activity and phosphatidate phosphatase activity. Involved in lipid import into cell; regulation of glutamatergic synaptic transmission; and regulation of postsynapse organization. Acts upstream of or within inner ear development. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic density membrane. Is expressed in genitourinary system and retina. Orthologous to human PLPPR4 (phospholipid phosphatase related 4).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced body weight, seizures, hyperexcitability of evoked fEPSP, and premature lethality around 3 weeks of age. [provided by MGI curators]
  • synonyms:
  • phospholipid phosphatase related 4,
  • Plppr4,
  • Lppr4,
  • MGD-MRK-34224,
  • mKIAA0455,
  • DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed,
  • PRG-1,
  • D3Bwg0562e,
  • lipid phosphate phosphatase-related protein type 4

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For