Primary Identifier | MGI:1270863 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 19072 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable oligopeptidase activity and peptide binding activity. Predicted to be involved in protein catabolic process. Located in cytoplasm and nucleus. Is expressed in several structures, including cranial ganglion; genitourinary system; heart ventricle; thymus primordium; and vibrissa. Orthologous to human PREP (prolyl endopeptidase). PHENOTYPE: Mice homozygous for a gene trap allele exhibit sex-dependent resistance to diet-induced obesity and adiposity. Mice heterozygous for a gene trap allele exhibit maternal inheritance influenced increase in body weight, organ weight, and adiposity. [provided by MGI curators] |