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Allele : a<21R> nonagouti; nonagouti 21 Oak Ridge

Primary Identifier  MGI:2384115 Allele Type  Radiation induced
Gene  a Inheritance Mode  Recessive
Strain of Origin  (101/Rl x C3H/Rl)F1 Is Recombinase  false
Is Wild Type  false
description  This allele has a null phenotype. Phenotypes of a alleles can be categorized in ~8 week old mice according to the amount of yellow, phaeomelanin, pigment vs black, eumelanic, pigment (J75206): MILD: Banded hairs are present on the dorsum, sides, and ventrum, with yellow hair around nipples, perineum, and behind ears. MODERATE: Banded hairs are present in all body regions, but with reduced yellow. Dorsum is moderately darker than sides adjacent to the ventrum. Yellow is prominent around nipples, perineum, and behind ears. UMBROUS-LIKE: Yellow is severely reduced along dorsal midline. Banded hair is present on the sides and ventrum but with reduced yellow. Yellow is also reduced around nipples, perineum, and behind ears. SEVERE: Yellow is severely reduced in dorsum, sides, and ventrum and moderately reduced around nipples, perineum, and behind ears. NULL: Hairs are completely black with no yellow banding. No yellow is present around nipples, perineum, and behind ears.
molecularNote  This mutation is a 11 nucleotide deletion starting at codon 118. It intorduces a shift in the reading frame after codon 121. Transcript expression levels from this allele are similar to wild-type.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • a<5FrSb>,
  • 5FrSb,
  • a<5FrSb>,
  • 5FrSb
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories

Trail: Allele