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Allele : Fosb<tm1Meg> FBJ osteosarcoma oncogene B; targeted mutation 1, Michael E Greenburg

Primary Identifier  MGI:1857395 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fosb
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette was inserted into exon 2, 5' to the sequences encoding the basic region and adjacent to the sequences encoding the transactivation domain. Northern blot analysis on RNA derived from serum-starved, stimulated embryonic fibroblasts derived from homozygous mice demonstrated that no detectable transcript is produced from this allele. Western blot analysis on these same cells confirmed that no detectable protein is encoded by this allele.
  • mutations:
  • Insertion
  • synonyms:
  • B<->,
  • FosB-,
  • B<->,
  • FosB-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

15 Publication categories

Trail: Allele