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Protein Coding Gene : Ppp1r18 protein phosphatase 1, regulatory subunit 18

Primary Identifier  MGI:1923698 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  76448
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable actin binding activity and phosphatase binding activity. Predicted to be located in cytoplasm and cytoskeleton. Is expressed in nervous system. Orthologous to human PPP1R18 (protein phosphatase 1 regulatory subunit 18).
PHENOTYPE: Mice homozygous for a null allele exhibit spleen hypoplasia, impaired CD4+ T cell homing, increased white blood cell, lymphocyte, and neutrophil, and reduced B and T cell numbers in the lymph nodes, peripheral lymph nodes, and spleen. [provided by MGI curators]
  • synonyms:
  • 2310014H01Rik,
  • MGI:2146864,
  • RIKEN cDNA 2310014H01 gene,
  • protein phosphatase 1, regulatory subunit 18,
  • MGI:2146745,
  • Ppp1r18,
  • expressed sequence AA407849,
  • expressed sequence AI450394,
  • AA407849,
  • AI450394

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For