| Primary Identifier | IPR000945 | Type | Family |
| Short Name | DBH-like |
| description | This family represents Dopamine beta-hydroxylase (DBH) and related enzymes, including tyramine beta-hydroxylase, MOXD1 homologue 1/2 and DBH-like monooxygenase protein 1/2 [].DBH, also known as Dopamine beta-hydroxylase, is a class of ascorbate-dependent enzymes from the catecholamine biosynthetic pathway that requires copper as a cofactor and uses ascorbate as an electron donor. DBH catalyses the conversion of dopamine to the neurotransmitter norepinephrine:3,4-dihydroxyphenethylamine+ ascorbate + O2= noradrenaline + dehydroascorbate + H2ODBH exists in both soluble (in chromaffin granules) and membrane bound forms. The protein functions as a homotetramer [, ].This entry includes monooxigenases found in metazoans, plants and fungi. |
