| Type | MGI:General | Description | homozygotes display aberrant cortical pyramidal neuron morphology, with an abnormally ballooned nucleus and a clearly demarcated nucleolus in layer V apical dendrites of mutant pyramidal neurons in layers II and III of the cerebral cortex display twisted configurations with abnormal winding and bifurcations in the proximal portion in addition, dendrites of mutant pyramidal neurons show disorganized microtubules with bundles being unevenly or peripherally localized inside the dendritic fibers pyramidal cells in layer III of the mutant cerebral cortex display a slight reduction in axon diameter |
