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Allele : Mmp28<tm1Mani> matrix metallopeptidase 28 (epilysin); targeted mutation 1, Anne M Manicone

Primary Identifier  MGI:3836773 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mmp28
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 4-7 and the coding portion of exon 8 were replaced with a neomycin selection cassette. This mutation was predicted to be a null allele because the remaining exons 1-3 only encode the proregion of the protein product. Protein product was absent in the airways of homozygote mice as determined by immunofluorescence staining.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Epilysin<->,
  • Epilysin<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele