Primary Identifier | MGI:3836773 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Mmp28 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 4-7 and the coding portion of exon 8 were replaced with a neomycin selection cassette. This mutation was predicted to be a null allele because the remaining exons 1-3 only encode the proregion of the protein product. Protein product was absent in the airways of homozygote mice as determined by immunofluorescence staining. |