| Primary Identifier | MGI:1890520 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 116733 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable ATP binding activity; ATP hydrolysis activity; and small GTPase binding activity. Involved in late endosomal microautophagy; multivesicular body assembly; and viral budding from plasma membrane. Acts upstream of or within endosome organization. Located in perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and nasal process. Orthologous to human VPS4A (vacuolar protein sorting 4 homolog A). PHENOTYPE: Mouse embryonic fibroblasts from mice heterozygous for Vps4a and Vps4b null alleles exhibit exhibit increased endo/lysosomal organelles with large multi-membrane structures. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
