| Primary Identifier | MGI:2176433 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 171543 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Involved in several processes, including negative regulation of autophagic cell death; negative regulation of autophagy; and positive regulation of cellular component organization. Acts upstream of or within negative regulation of apoptotic signaling pathway and positive regulation of apoptotic signaling pathway. Located in actin cytoskeleton and cytoplasm. Part of myosin complex. Is expressed in brain and pituitary gland. Orthologous to human BMF (Bcl2 modifying factor). PHENOTYPE: Mice homozygous for targeted knockout mutations show enlarged spleen, increased B cells and CD8-positive T cells, decreased B cells and T cells apoptosis, vagina atresia and hydrometrocolpos. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
