| Primary Identifier | MGI:105371 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 20745 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable calcium ion binding activity; cysteine-type endopeptidase inhibitor activity; and metalloendopeptidase inhibitor activity. Involved in central nervous system neuron differentiation and neuron migration. Located in neuromuscular junction; node of Ranvier; and sarcoplasm. Is active in postsynaptic density. Is expressed in several structures, including jaw; nervous system; sensory organ; skeletal musculature; and thymus primordium. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human SPOCK1 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1). PHENOTYPE: Mice homozygous for a targeted null mutation display no obvious morphological or behavioral abnormalities, are fertile, and have normal life spans. Adult homozygotes exhibit normal brain morphology and EEG recordings. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
