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Publication : The embryonic and adult mouse U1 snRNA genes map to different chromosomal loci.

First Author  Lund E Year  1988
Journal  Somat Cell Mol Genet Volume  14
Issue  2 Pages  143-8
PubMed ID  2894719 Mgi Jnum  J:9074
Mgi Id  MGI:57538 Doi  10.1007/BF01534399
Citation  Lund E, et al. (1988) The embryonic and adult mouse U1 snRNA genes map to different chromosomal loci. Somat Cell Mol Genet 14(2):143-8
abstractText  The linkage relationships of mouse adult (mU1a) and embryonic (mU1b) U1 snRNA genes were determined by analysis of the strain distribution patterns of two polymorphic variant RNAs, mU1a2 and mU1b3, in several recombinant inbred strain systems. The locus for mU1b3 RNA maps to the U1 gene cluster, Rnu1b, located near the center of chromosome 3, whereas the locus for mU1a2 RNA, Rnu1a2, is located in the proximal region of chromosome 12, tightly linked to D12-1. Moreover, the lack of linkage between Rnu1a2 and the locus for mU1a1 genes on chromosome 11 demonstrates that the mouse genome contains at least three clusters of U1 snRNA genes.
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