Primary Identifier | IPR042835 | Type | Family |
Short Name | PLEKHN1 |
description | Pleckstrin homology domain-containing family N member 1 (PLEKHN1), also known as CLPABP, is a cardiolipin phosphatidic acid binding protein that associates with microtubules and accumulates in RNAgranules, which contain cytochrome-c mRNA []. It binds to Bid (a pro-apoptotic protein), removes Bid from transient Bid-Bax complexes, and promotes apoptosis []. |