Primary Identifier | MGI:3784979 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Tom1l2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene trap vector pGT1lxf that contains the beta-geo cassette was inserted between exon 10 and 11. This allele is a reporter allele and a hypomorphic allele with reduced expression in the brain (80% reduction), liver (70% reduction) and spleen (50% reduction) of homozygotes as detected by semi-quantitative RT-PCR. |