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Publication : The staggerer gene curtails the reproductive life span of females.

First Author  Guastavino JM Year  1992
Journal  Behav Genet Volume  22
Issue  1 Pages  101-12
PubMed ID  1590727 Mgi Jnum  J:1960
Mgi Id  MGI:50484 Doi  10.1007/BF01066795
Citation  Guastavino JM, et al. (1992) The staggerer gene curtails the reproductive life span of females. Behav Genet 22(1):101-12
abstractText  Three studies were undertaken to investigate some features of the reproductive activity of female staggerer mice of the C57BL/6 strain. It was found that in the staggerer female, (1) vaginal opening and onset of vaginal estrous cycling were delayed; (2) the vaginal estrous cycle was irregular and characterized by abnormally prolonged diestrous and estrous phases, and (3) the reproductive life span of the mutant female was confined to a 3-month period after puberty. The abnormalities observed in sexual functions suggest a specific influence of the staggerer gene on reproductive activity.
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