|  Help  |  About  |  Contact Us

Allele : Tg(Thy1-MAPT*V337M)1Godt transgene insertion 1, Michel Goedert

Primary Identifier  MGI:3832877 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Thy1-MAPT*V337M)1Godt
Strain of Origin  (C57BL/6J x CBA/Ca)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The promoter was used to drive brain-specific expression of a cDNA that encodes the longest three-repeat human isoform with nucleotide substitutions resulting in the amino acid substitution of methionine for valine at position 337 (V337M). This mutation was originally identified in patients with frontotemporal dementias with Parkinsonism linked to chromosome 17 (FTDP-17). No line information was given.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(Thy1-MAPT*V337M)1Migo,
  • TauV337M,
  • Tg(Thy1-MAPT*V337M)1Migo,
  • TauV337M
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele