| Primary Identifier | MGI:1926194 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 57783 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables polyubiquitin modification-dependent protein binding activity. Involved in negative regulation of canonical NF-kappaB signal transduction; positive regulation of defense response; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system. Orthologous to human TNIP1 (TNFAIP3 interacting protein 1). PHENOTYPE: Mice homozygous for a null allele exhibit perinatal lethality associated with anemia and focal apoptosis in the fetal liver. Mice homozygous for a gene trap allele exhibit partial prenatal lethality and SLE-like inflammatory disease. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
