Primary Identifier | MGI:6888002 | Allele Type | Targeted |
Attribute String | Conditional ready, Inserted expressed sequence, No functional change, Reporter | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A vector containing the following elements was inserted into intron 1: the CAG promoter, a loxP site, the neomycin resistance gene, a STOP cassette, a second loxP site, a human PANX1 cDNA with C-terminal FLAG tag sequence, an IRES, the EGFP reporter gene and poly(A) signal sequence. The PANX1 and EGFP genes will only be expressed after cre-mediated deletion of the neo-STOP cassette. |