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Allele : Nlrp3<tm1Vmd> NLR family, pyrin domain containing 3; targeted mutation 1, Vishva M Dixit

Primary Identifier  MGI:3622094 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nlrp3
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 1-3 were replaced with a neomycin resistance cassette. Exon 3 contains the ATG and the entire pyrin domain; exons 1 and 2 encode the 5' UTR. RT-PCR failed to detect transcript in mutants.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Cias1<->,
  • Nalp3<->,
  • Cias1<->,
  • Nalp3<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

135 Publication categories

Trail: Allele