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Protein Coding Gene : Slc6a18 solute carrier family 6 (neurotransmitter transporter), member 18
Primary Identifier  MGI:1336892 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  22598
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables neutral L-amino acid:sodium:chloride symporter activity. Involved in neutral amino acid transport and renal amino acid absorption. Acts upstream of or within amino acid transmembrane transport. Located in apical plasma membrane and brush border membrane. Is expressed in several structures, including metanephros. Orthologous to human SLC6A18 (solute carrier family 6 member 18).
PHENOTYPE: Homozygous null mice are overtly normal but have increased blood pressure associated with impaired renal accumulation of glycine. [provided by MGI curators]
  • synonyms:
  • solute carrier family 6 (neurotransmitter transporter), member 18,
  • X transporter protein 2,
  • XT2,
  • MGI:2444902,
  • Slc6a18,
  • RIKEN cDNA D630001K16 gene,
  • Xtrp2,
  • D630001K16Rik
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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