| Primary Identifier | IPR035656 | Type | Domain |
| Short Name | Nostrin_SH3 |
| description | Nostrin is expressed in endothelial and epithelial cells and is involved in the regulation, trafficking and targeting of endothelial NOS (eNOS) []. It facilitates the endocytosis of eNOS by coordinating the functions of dynamin and the Wiskott-Aldrich syndrome protein (WASP) []. Increased expression of nostrin may be correlated to pre-eclampsia []. Nostrin contains an N-terminal F-BAR domain and a C-terminal SH3 domain. This entry represents the SH3 domain. |
