Primary Identifier | MGI:3582724 | Allele Type | QTL |
Gene | Pain2 | Inheritance Mode | Dominant |
Strain of Origin | C3H/HeN | Is Recombinase | false |
Is Wild Type | false |
description | This QTL is influenced by the caging effect. Pain2 shows high significance in individually-caged female animals. Homozygosity for C3H/HeN-derived alleles at Pain2 confers high autonomy in females with reduced penetrance (40%). However, heterozygosity for C58/J- and C3H/HeN-derived alleles at Pain2 is highly penetrant (97%) for low autonomy in females. |
molecularNote | This allele confers high pain compared to C58/J. |