| Primary Identifier | MGI:99914 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 226519 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables glycosphingolipid binding activity. Involved in several processes, including hair cell differentiation; hair follicle cell proliferation; and hair follicle morphogenesis. Acts upstream of or within neuron projection development. Located in basement membrane. Part of laminin-10 complex. Is active in neuromuscular junction and synaptic cleft. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human LAMC1 (laminin subunit gamma 1). PHENOTYPE: Embryos homozygous for a targeted null mutation lack development of basement membranes, migration of primitive endoderm cells out of the inner cell mass, and parietal yolk sac development, resulting in lethality by embryonic day 5.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
