Primary Identifier | MGI:3646469 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 244071 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables metallocarboxypeptidase activity and tubulin binding activity. Predicted to act upstream of or within proteolysis. Predicted to be located in cytosol. Is expressed in several structures, including central nervous system; early embryo; genitourinary system; liver; and retina. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy. Orthologous to human AGBL1 (AGBL carboxypeptidase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal response to herpes simplex virus (HSV) and vaccinia virus (VACV) infection. [provided by MGI curators] |