| Primary Identifier | MGI:1099436 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 19363 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable ATP-dependent activity, acting on DNA; double-stranded DNA binding activity; and single-stranded DNA binding activity. Predicted to contribute to four-way junction DNA binding activity. Acts upstream of or within blastocyst growth; positive regulation of cell population proliferation; and somite development. Predicted to be located in nucleus. Predicted to be part of Rad51B-Rad51C-Rad51D-XRCC2 complex. Predicted to be active in replication fork. Is expressed in cerebral cortex; cranial ganglion; dorsal root ganglion; neural retina; and ventral grey horn. Orthologous to human RAD51B (RAD51 paralog B). PHENOTYPE: Embryos homozygous for a knock-out allele are severely growth retarded and exhibit complete early embryonic lethality; interestingly, mutant embryos survive and develop further in a Trp53-null background. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
