| Primary Identifier | MGI:6113476 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Dennd1b |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Recombination of loxP sites that flanked exon 6 resulted in the deletion of these sequences in the germline. Deletion of exon 6 results in a loss of function of the gene by generating a frameshift from exon 5 to exons 7 - 10 with the introduction of a premature stop codon in exon 7. Western blot and qRT-PCR experiments confirmed the absence of expression from this allele. |
