Primary Identifier | MGI:2444233 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 213541 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables N6-methyladenosine-containing RNA reader activity. Involved in several processes, including hematopoietic stem cell proliferation; regulation of gene expression; and spermatogonial cell division. Located in cytoplasm and nucleus. Is expressed in brain; intestine; and liver. Orthologous to human YTHDF2 (YTH N6-methyladenosine RNA binding protein F2). PHENOTYPE: Mice homozgyous for a knock-out allele exhibit female, but not male, infertility and preweaning lethality that is background sensitive. Homozygous KO male mice are hypo-fertile. [provided by MGI curators] |